Liz Buchanan BVSc MRCVS
Keymaster
Hello - yes, black spots on the prepuice are definitely noteworthy because they can turn out to be infection / yeast infection / cell death or cancer amongst other things, which your vet would want to know about. Cancer, when it occurs, is sometimes completely painless. Paticularly if they are worrying at it or struggling to urinate, this may need to be seen quickly as this is in a very sensitive part of the body.
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