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Confused, Histopathology

Published on: August 08, 2025 • By: alloydster · In Forum: Dogs
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alloydster
Participant
August 08, 2025 at 06:00pm
Histopathology came back benign- No evidence of neoplasia, differentials considered include immune-mediated inflammation, a regressing histiocytoma or resolving furunculosis. Inflammatory dermal mass composed of moderate numbers of lymphocytes and histiocytes, with fewer neutrophils and plasma cells. There is mild dermal fibrosis. When removed small mass on dogs chin was maybe a little larger than a pencil eraser. Was healing well, not now starting to form hard bump again. Anyone have something similar? Vet thought surgery would be curative. Have an appointment next week for her to check!
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Liz Buchanan BVSc MRCVS
Keymaster
August 08, 2025 at 07:31pm
Hello and thank you for this interesting history.  Lumps can broadly be split into 2 categories, inflammatory and cancerous.  While the term 'benign' means 'not cancerous', some non-cancerous lumps can still be persistent and troublesome. My advice is what you seem to be doing - to go back to your vet and try to understand. If they had an external pathologist, they may benefit considerably from speaking to them.  I used to find mine extremely helpful when it came to getting practical meaning from these descriptive lab sheets.  Try to understand why the sample was not diagnostic (did not give an answer).  Whether more samples or trial treatment would be most useful at this point. Please will you let us know how you get on?  
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Malcom_Ketheridge
Participant
August 15, 2025 at 04:06pm
Yeah, histopath stuff can be bloody confusing. It’s basically the lab looking at a bit of tissue under the microscope to see what’s happening at a cell level. The wording can sound scarier than it is, so best bet is to have a chat with your vet — they can break it down in plain English and let you know what it really means for your pup.
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Malcom_Ketheridge
Participant
August 15, 2025 at 04:06pm
Yeah, histopath stuff can be bloody confusing. It’s basically the lab looking at a bit of tissue under the microscope to see what’s happening at a cell level. The wording can sound scarier than it is, so best bet is to have a chat with your vet, they can break it down in plain English and let you know what it really means for your pup.
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