Liz Buchanan BVSc MRCVS
Keymaster
Frequently, these are simply a build-up of keratin (hard skin) on the bottom of the foot, but why would it suddenly happen in just one toe? This could be due to a change in gait e.g. due to arthritis, causing a reluctance for weight-bearing in that direction. Other possibilities include fungal disease or a tumour. Because we don't know what the change represents in your cats' case, we would definitely advise talking it over with your vet. Best of luck.
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