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Kidney disease cause

Published on: December 11, 2025 • By: torcatlover · In Forum: Cats
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torcatlover
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December 11, 2025 at 07:10pm
Hi looking for vet thoughts I know hard to say without full diagnostics. I had two cats we lost one to what the vets said was renal disease last week but 3 weeks before that we had other cat in hospital with pancrititis. Im so worried something has caused both these illness. I did notice some visible mould on some food left out (not ours) 4 weeks before all this. Our cats could have got access to it but other than that cannot think of what may be the link, we moved house 6 months ago so maybe something new in the environment. Vets said they think the two serious illness conditions are not related but inlm struggling with that fact as they were so close. Cat 1 - Is now home and well. Vet notes - Clinical examination revealed marked cranial organomegaly with associated focal abdominal pain. A grade 1/6 left parasternal murmur with no arrhythmia or gallop sound was detected on thoracic auscultation. Peripheral pulses were hyperdynamic; mucus membranes were tacky with rapid capillary refill time. Mild reduced skin turgor was observed. Investigations included blood tests (venous blood gas haematology, serum biochemistry), imaging (abdominal ultrasound) and FNA sampling of the pancreas, mesenteric lymph nodes and free peritoneal fluid. Pertinent results: Blood tests were supportive of inflammation (neutrophilia 19.37x109/L; RI 3.0-13.4, with left shift and 3+ toxicity). Abdominal imaging revealed: Marked acute pancreatopathy - the severe nature of this and loss of normal parenchymal texture and shape, in addition to associated lymphadenopathy, was most concerning for neoplastic disease (e.g. pancreatic adenocarcinoma, lymphoma) although inflammatory disease was also considered possible. Associated marked peritonitis, peritoneal effusion and mesenteric and coeliac lymphadenopathy. Severe duodenitis and mild small intestinal enteropathy. Non-specific hepatopathy. Cytology of the pancreas was consistent with inflammation; no pancreatic epithelial cells were aspirated and therefore an underlying neoplasia cannot be excluded. Cytology of free peritoneal fluid revealed a neutrophilic exudate (consistent with inflammation). Cytology of mesenteric lymph nodes was most consistent with eosinophilic lymphadenitis. Prognosis and treatment recommendations: Our investigations are most suggestive of an acute pancreatopathy (disease process affecting the pancreas) as the cause of …. clinical signs; our sampling was most consistent with acute inflammation and supports a diagnosis of acute pancreatitis, however, no pancreatic epithelial cells were aspirated in the FNA sample and so an underlying neoplastic process (cancerous cause) cannot be completely excluded. Lymph node sampling revealed possible eosinophilic lymphadenitis - this is is unusual as a direct reaction to acute pancreatitis; eosinophilic inflammation may be primary or occur secondary to regional eosinophilic inflammation, such as that associated with hypersensitivity reactions, parasitic infections, or neoplastic/paraneoplastic processes. Further investigations to determine the underlying cause were not performed in ….case. In the majority of cats (>80%) of cats with pancreatitis, no cause is identified and treatment involves symptomatic and supportive care of associated clinical signs. Indie responded well to supportive management for acute pancreatitis and began eating with reliable appetite while hospitalized; she was discharged to continue her recovery at home. Many cats with acute pancreatitis can demonstrate good recovery (60-90%), however others will develop chronic or recurrent pancreatitis that may require ongoing supportive care to maintain appetite and manage any associated pain or discomfort. A proportion of cats with pancreatitis do not respond to supportive treatment and may be euthanised due to persistent clinical signs Cat 2 - about two months ago was asking for food constantly, seemed to have a big increase in appetite, I thought she was losing weight on back end but vets on vaccinations in July did not seem concerned . She was 12 over the last two years of her life has had skin issues, lots of sores. Vets thought she had developed flea bite allergies and she often had steriod injections for them. About two weeks ago her appetite reduced, eating on and off and she seemed less active but okay (I think I should of took her in then) then a the day before she was put to sleep she suddenly crashed stopped eating, lying in the same point, drinking and urinating lots. we took her to vets they said she had enlarged kidneys, lots of fluid in and around them and was dehydrated and anemic (sorry will try get more notes on this) by the time we took her to vets you could feel her spine but it feels like she was suddenly like this (but aware that somehow I must of missed the dramatic weight loss ). She had bravecto a week before the crash but it was prescribed previously in July Sorry for long post but any insights may help me process all this
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