Bone cancer Bernese mountain dog

3.5-year-old Bernese Mountain Dog with intermittent front leg lameness for several months. Pain improves with anti-inflammatory/pain medication and he still has good and bad days, runs normally.   Vet found a bone lesion in the proximal humerus on radiographs and referred us to an orthopedic specialist. Bloodwork mainly shows inflammatory changes.   Would anyone experienced with veterinary radiology or orthopedic cases be willing to look at these X-rays and share opinions on possible differentials (bone cyst, inflammation, OCD, tumor, etc.) while we wait for specialist consultat ion?

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Hello and thankyou for sharing these fascinating radiographs which do appear to show an area of relative lucency - or lack of bone density - in the humerus.  Unfortunately we are not in the business of giving second opinions; a second opinion vet is one who has all the information that your vet has available to them and more on top - usually the 'more' comes from having specialist knowledge of that subject or access to superior diagnostic tools.  In this case, I have substantially less information available to me than your vet has to them, and they are not sure;  it would be unprofessional of me to offer a second opinion (the RCVS issue a code of professionalism that we all have to follow).  There may be orthopaedic vets around on this website who might put their oar in later. However, I think it's very positive that your vet hasn't jumped to conclusions in this scenario but referred the picture appropriately - it's usually sign of a good first-opinion vet when they'll admit that they don't know!   Indeed I would also be concerned about cancer or oesteopenia and I, like your vet, would have sent this picture to a specialist.  I know that the waiting period is going to be a very anxious one for you and wish you well; I would also be fascinated to hear the diagnosis if one comes back to you and you feel ready to share it.

Otherwise, wishing all of you the very best with your obviously much loved dog.